This study addresses several significant gaps in the literature by (1) examining peer victimization, perceptions of school violence and crime, and TDV victimization among LGBTQ and non-LGBTQ high school students as predictors of anxiety and suicidality; (2) evaluating the extent to which victimization, perceptions of school violence and crime, and TDV moderate the association between sexual orientation and the aforementioned mental health issues; and (3) testing victimization, perceptions of school violence and crime, and TDV as school-level (between-school) predictors of these outcomes.